Zhang D.W., Garuti R., Tang W., Cohen J.C., and Hobbs H.H. (2008) Structural Requirements for PCSK9-Mediated Degradation of the Low Density Lipoprotein Receptor. Proc. Natl. Acad. Sci. U S A. 105:13045-50.

Wang J., Zhang D.W., Lei Y., Xu F., Cohen J.C., Hobbs H.H., and Xie X.S. (2008) Purification and reconstitution of sterol transport by native mouse ABCG5 and ABCG8. Biochemistry. 47:5194-204.

Zhang D.W., Lagace T.A., Garuti R., Zhao Z., McDonald M., Horton J.D., Cohen J.C., and Hobbs H.H. (2007) Binding of PCSK9 to EGF-A repeat of LDL receptor decreases receptor recycling and increases degradation. J. Biol. Chem. 282: 18602-12.

Wang J., Sun F., Zhang D.W., Ma Y., Xu F., Belani J.D., Cohen J.C., Hobbs H.H., and Xie X.S. (2006) Sterol transfer by ABCG5 and ABCG8: in vitro assay and reconstitution. J. Biol. Chem. 281: 27894-904. 

Zhang D.W., Graf G.A., Gerard R.D., Cohen J.C., and Hobbs H.H. (2006) Functional asymmetry of nucleotide binding domains (NBD) in ABCG5 and ABCG8. J. Biol. Chem. 281: 4507-16.

Zhang D.W., Nunoya K., Vasa M., Gu H.M., Cole S.P.C., and Deeley R.G. (2006) Characterization of the role of polar amino acid residues within predicted transmembrane helices 10 and -16 in determining the substrate specificity of Multidrug Resistance Protein 1 (ABCC1). Drug Metab. Dispos. 34: 539-46.

Zhang D.W., Nunoya K., Vasa M., Gu H.M., Theis A., Cole S.P.C., and Deeley R.G. (2004) Transmembrane helix 11 of multidrug resistance protein 1 (MRP1/ABCC1): identification of polar amino acids important for substrate specificity and binding of ATP at nucleotide binding domain 1. Biochemistry. 43: 9413-25.

Situ D., Haimeur A., Conseil G., Sparks K.E., Zhang D.W., Deeley R.G., and Cole S.P.C. (2004) Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transporter. J. Biol. Chem. 279: 38871-80.

Zhang D.W., Gu H.M, Situ D., Haimeur A., Cole S.P.C., and Deeley R.G. (2003) Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state. J. Biol. Chem. 278: 46052-63.

Zhang D.W., Gu H.M, Vasa M., Muredda M., Cole S.P.C., and Deeley R.G. (2003) Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of Multidrug Resistance Protein 3 (ABCC3). Biochemistry. 42: 9989-10000.

Nunoya K., Grant C.E., Zhang D.W., Cole S.P.C., and Deeley R.G. (2003) Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1). Drug Metab. Dispos. 31: 1016-26.

Qian Y.M., Grant C.E., Westlake C.J., Zhang D.W., Lander P.A., Shephard R.L., Dantzig A.H., Cole S.P.C., and Deeley R.G. (2002) Photolabeling of human and murine multidrug resistance protein 1 with the high affinity inhibitor [125I]LY475776 and azidophenacyl-[35S]glutathione. J. Biol. Chem. 277: 35225-35231.

Zhang D.W., Cole S.P.C., and Deeley R.G. (2002) Determinants of the substrate specificity of multidrug resistance protein1 (MRP1): Role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17. J. Biol. Chem. 277: 20934-20941.

Zhang D.W., Cole S.P.C., and Deeley R.G. (2001) Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17. J. Biol. Chem. 276: 34966-34974.

Zhang D.W., Cole S.P.C., and Deeley R.G. (2001) Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines. J. Biol. Chem. 276: 13231-13239.